Mushroom Defense Formula


Unique blend of five medicinal mushroom extracts, formulated to provide deep immune system support.

  • Support deep immune system health*
  • Boosts natural levels of energy*
  • Balances hormones for enhanced mental clarity*
  • Helps to regulate blood sugar levels*

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Mushroom Defense Formula

Mushroom Defense Formula is a unique blend of five medicinal mushroom extracts, formulated to provide deep immune system support.* Made with organic mushroom fruiting bodies with no added fillers, starch, grains or mycelium. Extracted with only hot water, each serving is verified to contain more than 30% Beta-D-glucans.

Lab Tested
Veggie Capsule
GMP Certified
Made in the USA
The Natural Immunity Booster

The Natural Immunity Booster

Did you know that the humble mushroom has the ability to significantly boost your body’s immunity? Mushrooms fight disease with helpful sugars in the fungi’s cell walls, called beta glucans. They help the body by altering white blood cells and modulating immune function. This can improve immune response to viruses and diseases. In addition, mushrooms deliver antioxidants to defend against free radicals, which can damage cells and risk cancer – and reduce inflammation in the body that causes disease.

Pure and Potent Medicinal Mushrooms

Pure and Potent Medicinal Mushrooms

This medicinal blend was formulated to provide deep immune system support. It features…

  • 5 Mushroom Extracts: Formulated for immune support*
  • Hot Water Extracted: For increased bioavailability
  • Over 30% Beta-D Glucans: Verified for high potency
  • Less than 3% Starch: No added fillers or grains
Extracts from Genuine Fruiting Bodies

Extracts from Genuine Fruiting Bodies

Made from top-quality organic and non-GMO ingredients.

No fillers.

No starch.

No grains.

No mycelium.


Know What You’re Putting in Your Body

Science-Based Formulation
Lab Tested for Purity and Potency
All Organic Ingredients
All Non-GMO Ingredients
GMP Certified Manufacturing

Clinical Research

Reishi Mushroom

Reishi Mushroom

Also known as Ganoderma lucidum, Lingzhi, Yeongji, Mushroom of Immortality

Reducing Inflammation: Anti-inflammatory effects mediated through the inhibition of NF-kappaB and AP-1 signaling pathways.

  • Dudhgaonkar S1, Thyagarajan A, Sliva D. Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum. Int Immunopharmacol. 2009 Oct;9(11):1272-80.

Fights Cancer: Suggested as adjunct to treatment for enhancing tumor response and stimulating immunity. In vitro appears to induce tumor cell death.

  • Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev. 2016 Apr 5.

Well Being & Energy: Significantly effective in increasing subjective well being and reducing fatigue. Particularly as adverse symptoms of a disease state decline.

  • Tang W, Gao Y, Chen G, Gao H, Dai X, Ye J, Chan E, Huang M, Zhou S. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. J Med Food. 2005 Spring;8(1):53-8.

Chaga Mushroom

Chaga Mushroom

Also known as Inonotus obliquus

Increasing Immunity: In early studies, stimulated the immune system, reduced inflammation, and reduced fatigue.

  • Glamoclija J, Ciric A, Nikolic M, et al. Chemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal “mushroom”. J Ethnopharmacol. Mar 13 2015;162:323-332.

Anticancer Effects: Initial studies showed inhibited cancer progression and ability to kill cancer cells selectively.

  • Anticancer effects of fraction isolated from fruiting bodies of Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae): in vitro studies.

Shiitake Mushroom

Shiitake Mushroom

Also known as Lentinula edodes

Chemotherapy and Cancer: Significant advantage over chemotherapy alone in terms of survival. Considered to prolong survival and improved quality of life, in combination with chemotherapy.

  • Nakano H, Namatame K, Nemoto H, Motohashi H, Nishiyama K, Kumada K. A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group. Hepatogastroenterology. 1999 Jul-Aug;46(28):2662-8.
  • Oba K, Kobayashi M, Matsui T, Kodera Y, Sakamoto J. Individual patient based meta-analysis of lentinan for unresectable/recurrent gastric cancer. Anticancer Res. 2009 Jul;29(7):2739-45.

Antibiotic and Antiviral: Provided as source of proven medicinal compounds, including polysaccharides, as antibiotic, anti-carcinogenic and antiviral.

  • Bisen PS, Baghel RK, Sanodiya BS, Thakur GS, Prasad GB. Lentinus edodes: a macrofungus with pharmacological activities. Curr Med Chem. 2010;17(22):2419-30.

Maitake Mushroom

Maitake Mushroom

Also known as Trametes versicolor

Immune Strength: Associated with both immunologically stimulatory and inhibitory measurable effects, particularly for patients undergoing chemotherapy.

  • Deng G, Lin H, Seidman A, Fornier M, D’Andrea G, Wesa K, Yeung S, Cunningham-Rundles S, Vickers AJ, Cassileth B. A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects. J Cancer Res Clin Oncol. 2009 Sep;135(9):1215-21. doi: 10.1007/s00432-009-0562-z. Epub 2009 Mar 1.

Cancer Tumor Fighting: Shown to act directly on tumor cells, modulating different cellular processes involved in the development and progression of cancer.

  • Alonso EN, Ferronato MJ, Gandini NA, Fermento ME, Obiol DJ, López Romero A, Arévalo J, Villegas ME, Facchinetti MM, Curino AC. Antitumoral Effects of D-Fraction from Grifola Frondosa (Maitake) Mushroom in Breast Cancer. Nutr Cancer. 2016 Nov 28:1-15.

Turkey Tail Mushroom

Turkey Tail Mushroom

Also known as Grifola frondosa, hen-of-the-woods, ram’s head, sheep’s head

Fighting cancer: Positive results seen in the adjuvant treatment of gastric, esophageal, colorectal, breast and lung cancers.

  • Fisher M, Yang LX. Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy. Anticancer Res. 2002 May-Jun;22(3):1737-54.
  • Torkelson CJ1, Sweet E, Martzen MR, Sasagawa M, Wenner CA, Gay J, Putiri A, Standish LJ. Phase 1 Clinical Trial of Trametes versicolor in Women with Breast Cancer. ISRN Oncol. Epub 2012 May 30.

Supports Immunity: Found supportive of overall immunity, particularly with weakened immune state, such as cancer or AIDS.

  • Guggenheim AG1, Wright KM1, Zwickey HL1. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44.


Suggested Use

Suggested Use

For immune system maintenance, take 2 capsules per day. For therapeutic use, take 4 capsules per day or as recommended by your healthcare practitioner.

No added fillers, starch, grains or mycelium.

Be Safe

Be Safe

Do not exceed recommended serving size. Do not take if you are pregnant or nursing, or under the age of 18. If you are currently taking any prescription medication, consult your physician prior to use. Immediately discontinue use and call your doctor if you experience any adverse reaction. Keep out of reach of children.


Where is your product manufactured?

Mushroom Defense is manufactured in California at a GMP (general manufacturing practices) certified facility, inspected by the FDA. During manufacturing, ingredients are tested for purity and potency and then tested again upon final encapsulation.

What is the capsule made of? Is there any animal products in the capsule?

Our capsules are vegetarian-grade capsules (“veggie-caps”) with NO animal-based gelatin and are approved by the Vegetarian Society, Vegan Action (U.S.), non-GMO Project verified, and Kosher certified as well as certified Halal. They are preservative free, allergen free, gluten free, sugar free and starch free.

Is Mushroom Defense manufactured in a GMP (general manufacturing practices) certified facility?

Yes! Mushroom Defense is manufactured in a GMP certified facility in California. This ensures the highest standard of quality control and purity testing.

How many capsules come in one bottle?

Mushroom Defense contains 90 capsules per bottle, which is good for 45 day supply.

Are the ingredients in Mushroom Defense from fruiting bodies or mycelium of mushrooms?

All our mushroom ingredients are extracts from genuine fruiting bodies – NOT from mycelium. In fact, Mushroom Defense contains NO fillers, starch, grains, or mycelium at all. Our formula is made from top-quality organic and non-GMO ingredients.

What kind of extraction method is used for ingredients in Mushroom Defense?

All the mushroom extraction in Mushroom Defense are Hot Water Extracted. This increases the bioavailability of benefits from these mushrooms. This is the extraction method most often used in Traditional Chinese Medicine, and its benefits and continued use is backed by science.


Our goal is to support you in your health, and at the same time ensure you are happy with your purchase. We offer these guarantees so you can be certain that you will be totally satisfied with our products and services.

Our Product Guarantee

Our Product Guarantee

Money back for 60 days if you’re not happy.

DailyNutra wants you to be completely satisfied with your purchase, and that is why we offer a 60-day money back guarantee from the date you ordered your products. We’d love to know why you didn’t like it, but only if you want to share. We just ask you to return the unused portion of the product even if that’s just an empty bottle. Read the details of how it works.

Our Customer Support Guarantee

Our Customer Support Guarantee

We respond in 48 hours or less.

We care about our customers and will respond to your message quickly, usually in less than 24 hours. Our email support desk is a great way to get help. If you need immediate support, call us toll-free at 1 (800) 506-8959.

Our Shipping Guarantee

Our Shipping Guarantee

Your order leaves our warehouse in 48 hours or less.

We want you to get your supplements as soon as possible. That’s why we typically ship our products from our warehouse in as little as 24 hours, and never more than 48 hours!

Our Transparency Guarantee

Our Transparency Guarantee

You know exactly what you’re putting in your body.

We provide extensive verification of our product’s purity and potency. On our label’s Supplement Facts, we list all ingredient amounts with active compounds, and we never use “proprietary blends”. Every ingredient we use is lab tested for potency, as well as heavy metals and microbial activity.

Our Privacy Guarantee

Our Privacy Guarantee

We won’t share your information.

We care about your privacy. We do not share your email and personal information with anyone. All customer information is transmitted and stored securely. If you are subscribed to any of our email lists, you may unsubscribe at anytime.

Our Security Guarantee

Our Security Guarantee

Your information is safe with us.

Our all of your customer information and our entire website is transmitted over secure SSL 256-bit encryption. We enforce strong passwords and perform regular security audits. Your credit card information is never stored on our server and is only transmitted to our payment processor Stripe for verification.

Our Quality Guarantee

Our Quality Guarantee

We offer the best supplements money can buy.

We take extensive care to produce the highest quality products at all levels. Here is a partial list of the activities we do on regular basis to ensure the highest quality and safest products available.

  • We only use General Manufacturing Practices (GMP) certified manufacturing
  • All our ingredients are third-party lab tested for active ingredient potency, as well as heavy metals and microbial activity.
  • All our bottles use air-tight safety seals as well as cap tamper protection seals
  • Expiration dates are clearly printed on all bottles, boxes and master packs
  • We pack our bottles in recyclable boxes for extra protection from damage or temperature
  • We use temperature controlled warehouses and shipping whenever possible to ensure no heat damage
  • Supplement Facts and Warning labels are clearly posted
  • We provide customers with FAQs on safe usage